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Introduction to RBPEqBind2 months ago
Overview | Introduction | Background | Motivation | Mathematical Model | Reference | Installation | Setup | Data Loading | Loading RBP Models | Visualizing Raw Models | Setting Affinity Ranges | RNA-RBP Binding Simulations | Scenario 1: RBPs Binding to a Single RNA Target at Fixed Concentrations | Generating or Loading RNA Sequence | Running the Simulation | Visualization | Per-Position Binding Profile | Heatmap Visualization | Exporting Results | Scenario 2: RBP Binding with Varying Concentration Grid | Running Grid Simulation | Competition Grid Plot | Scenario 3: RBPs Binding to Multiple Target RNAs | Scenario 4: RBPs Binding to Multiple Target RNAs Across Different Concentrations | Session Info
Introduction to RBPSpecificity4 months ago
Overview | Introduction | Background | Reference | Workflow Integration | Sample Data | RBNS Data | eCLIP Data | Setup | In Vitro Specificity from Pre-computed Enrichment Data (RBNS) | Loading RBNS Data | Calculating Specificity and Sensitivity for All Four RBPs | Visualization | Specificity Distribution Plots | Sensitivity Profile Plots | Cellular Specificity from De Novo Enrichment (eCLIP) | Loading Peak Data | Running motifEnrichment Pipeline | Comparing In Vitro (RBNS) vs. Cellular (eCLIP) Specificity | Session Info